Pyrogallol

Polarography of Tin ( IV ) - Pyrogallol Complexes .

Pyrogallol: A novel tool for screening immunomodulators

Objective: To induce immunosuppression in rats by pyrogallol and to develop a novel model to screen the immunomodulatory activity of a known agent. Material and Methods: In order to induce immunosuppression, pyrogallol was daily administered to rats for 7 days in different doses (10, 25, 50 and 100 mg/kg, i.p.). On Day 7 and 13, the rats were sensitized with sheep red blood cells (SRBC) to asse...

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists

Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin and fenoldopam, display agonistic activity against GPR35.

Antimicrobial activity of catechol and pyrogallol as allelochemicals.

Catechol and pyrogallol are allelochemicals which belong to phenolic compounds synthesized in plants. Their antimicrobial activities were investigated on three bacteria (Pseudomonas putida, Pseudomonas pyocyanea, Corynebacterium xerosis) and two fungi (Fusarium oxysporum, Penicillium italicum) phytopathogenic species as test organisms using the disc diffusion method. Both catechol and pyrogallo...

Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin.

The aim of this study was to investigate the oxido-reductive reactions of human hemoglobin with pyrogallol and the metabolism of pyrogallol by the protein, which contains a protoporphyrin IX like cytochrome P-450. Pyrogallol, having three hydroxy groups at the adjacent positions in the benzene ring, oxidized human oxyhemoglobin to methemoglobin and reduced human methemoglobin to oxyhemoglobin. ...